The effect of perioperative immunonutrition on surgical complications and quality of life in patients with head and neck cancer

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dc.authorid0000-0002-8198-478X
dc.contributor.authorBaşmısırlı, Eda
dc.contributor.authorŞahin, H.
dc.date.accessioned2025-04-16T21:40:04Z
dc.date.available2025-04-16T21:40:04Z
dc.date.issued2021
dc.departmentFakülteler, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü
dc.description.abstractRationale: This intervention study, which was planned as a prospective randomized controlled, was conducted to compare the effects of periop erative nutritional support with immunonutrition and standard enteral products on postoperative complications and quality of life in patients with head and neck cancer (HNC). Methods: Between April February 2019 and February 2021, the study was conducted in Erciyes University Faculty of Medicine and Kayseri City Hospital Otolaryngology and Head Neck Surgery Clinic with 34 hospital ized patients with a diagnosis of HNC. Five days before surgery and 10 days postoperatively, immunonutrition support was given to the intervention group (n¼17), and standard enteral nutrition support was given to the control group (n¼17). Five days before surgery, 10th and 40th post operative days; body analyzes were made, food consumption records were taken, Nutritional Risk Score (NRS) -2002 and quality of life scales (EORTC QLQ-C30, EORTC QLQ-H & N35) were applied, biochemical parameters, complications, length of hospital stay and nutritional support has been recorded. Results: Although there was no difference in energy intake between the intervention and control groups on the preoperative and 10th post operative day, protein intake was significantly higher in the intervention group on the 10th postoperative day (p0.05). The NRS-2002 scores of the inter vention and control groups increased on the 10th postoperative day (2.65±1.37, 3.18±1.13, respectively) compared to the preoperative period (2.0±1.28, 2.65±1.37, respectively), and decreased again on the 40th day (2.06±1.30, 2.71±1.31, respectively, p>0.05). Serum albumin levels decreased on the 10th postoperative day compared to the preoperative period, both in the intervention group (3.86±0.51 mg/dL) and in the control group (3.60±0.41 mg/dL, p0.05). Conclusion: In conclusion, compared to the perioperative standard enteral nutritional support, immunonutrition support provides an improvement in some components of quality of life scales. However, it has been shown that studies with longer follow-up and larger samples are required to observe its effect on complications. Disclosure of Interest: None declared
dc.identifier.endpage750
dc.identifier.pmidN/A
dc.identifier.scopusN/A
dc.identifier.scopusqualityN/A
dc.identifier.startpage750
dc.identifier.urihttps://hdl.handle.net/20.500.14440/1356
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorBaşmısırlı, Eda
dc.language.isoen
dc.relation.ispartofEspen 2021
dc.relation.publicationcategoryKonferans Öğesi - Ulusal - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Kurum_20250417
dc.subjectHead and neck cancer
dc.titleThe effect of perioperative immunonutrition on surgical complications and quality of life in patients with head and neck cancer
dc.typeConference Object

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