Comparison of the sealing ability of apical plug materials in simulated open apices: An in vitro study

Background: The aim of this study was to evaluate the microleakage of apical plugs made of four different materials in simulated immature teeth. Materials and Methods: Ninety extracted single-rooted teeth were selected and randomly divided into six groups according to the materials used: NeoMTA, EndoSequence Bioceramic Root Repair Material Fast Set Putty (BC RRM-FS), Biodentine, Endo Repair, negative control, and positive control group. Microleakage was evaluated by using a stereomicroscope to assess the penetration of methylene blue solution. Data were analyzed using descriptive statistics and Pearson’s Chi-square test (P < 0.05). Results: EndoRepair group showed the highest leakage, and NeoMTA group exhibited the best sealing ability of apical plugs. The sealing ability of Biodentine was similar to NeoMTA and BC RRM-FS. On the other hand, the sealing ability of BC RRM-FS significantly lower than NeoMTA, but it provided a better sealing than EndoRepair. Conclusion: According to the results of this study, NeoMTA and Biodentine can be used safely as apical plug material in single-session apexification in immature teeth. The BC RRM-FS, on the other hand, provided an acceptable sealing, although not as successful as the NeoMTA. However, the sealing properties of Endo Repair need to be improved.