Could juice from Viburnum opulus potentially prevent the formation of kidney stones? (an anımal study)

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dc.contributor.authorÖmerli, Ayşe
dc.contributor.authorUlger, Harun
dc.contributor.authorNisari, Mehtap
dc.contributor.authorYay, Arzu
dc.contributor.authorKaratoprak, Gokce Seker
dc.date.accessioned2025-02-24T16:35:52Z
dc.date.available2025-02-24T16:35:52Z
dc.date.issued2023
dc.departmentNuh Naci Yazgan
dc.description.abstractThe principal objective of this inquiry was to explore the potential impact of Viburnum opulus L. fruit juice in mitigating the occurrence of kidney stone formation within a rat model induced experimentally to develop kidney stones. Twenty Sprague Dawley rats were used in the study. They were placed in metabolic cages, with one rat per cage. Urine samples were collected every day during the study period. Biochemıcal values were measured in urine and blood. The rats were sacrificed, and their kidneys were removed and evaluated histopathologically after staining with Hematoxylin-Eosin (HE) and Pizzolato’s (PZ) staining methods. The biochemical parameters observed in the urine samples collected from the experimental group of rats exhibited more excellent proximity to the negative control group’s corresponding values than those of the positive control group. Upon microscopic examination of histological sections, a notable resemblance in histological architecture was discerned between the experimental and negative control groups. Additionally, a reduction in the incidence of stone formation was observed in the experimental group when contrasted with the positive control group. In light of the outcomes elucidated herein, it can be deduced that the administration of Viburnum opulus (VO) water engenders an augmenting impact on citrate levels. This elevation in citrate concentration holds potential significance as it demonstrates the potential to curtail crystal formation. Notably, citrate ions exhibit an inhibitory role in the genesis of calcium oxalate (CaOx) crystals, thereby contributing to the prevention. © 2023 Visagaa Publishing House.
dc.identifier.doi10.53365/nrfhh/170923
dc.identifier.endpage386
dc.identifier.issn2583-1194
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85168968586
dc.identifier.scopusqualityQ2
dc.identifier.startpage379
dc.identifier.urihttps://doi.org/10.53365/nrfhh/170923
dc.identifier.urihttps://hdl.handle.net/20.500.14440/643
dc.identifier.volume3
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherVisagaa Publishing House
dc.relation.ispartofNatural Resources for Human Health
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20250201
dc.subjectGuelder rose juice
dc.subjectKidney stone
dc.subjectUrolithiasis
dc.subjectViburnum opulus
dc.titleCould juice from Viburnum opulus potentially prevent the formation of kidney stones? (an anımal study)
dc.typeArticle

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