Evaluation of the Efficacy of 2% Chlorhexidine in Combination with Passive Ultrasonic Irrigation on Enterococcus faecalis Biofilm

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dc.authorid, Bertan/0000-0001-9192-5487
dc.authoridTezcan Ulger, Seda/0000-0002-0823-3680
dc.authoridTOPCUOGLU, Huseyin Sinan/0000-0002-2581-7127
dc.contributor.authorKesim, Bertan
dc.contributor.authorUlger, Seda Tezcan
dc.contributor.authorTopcuoglu, Huseyin Sinan
dc.contributor.authorAslan, Gonul
dc.contributor.authorKurnaz, Nurbanu
dc.contributor.authorSagsen, Burak
dc.date.accessioned2025-02-24T17:19:09Z
dc.date.available2025-02-24T17:19:09Z
dc.date.issued2020
dc.departmentFakülteler, Diş Hekimliği Fakültesi, Endodonti Ana Bilim Dalı
dc.description.abstractObjective: This study aimed to evaluate the combined effectiveness of 2% chlorhexidine (CHX) and passive ultrasonic irrigation (PUI) against Enterococcus faecalis (E. faecalis) biofilm. Materials and Methods: The root canals of 66 single-rooted extracted human mandibular premolar teeth (n=66) were enlarged up to a size of 40/0.06 taper and autoclaved. Fifty-nine roots were inoculated with E. faecalis and incubated for 4 weeks, whereas 7 roots served as the negative control group and were filled with sterile brain heart infusion broth. The remaining specimens (n=59) were assigned into 4 experimental groups (n=13) and a positive control group (n=7): CHX via standard needle irrigation (SNI), sodium hypochloride (NaOCl) via SNI, CHX via PUI, NaOCl via PUI and non-treated positive controls. Bacteriological samples were collected before and after the intervention, and microbiological analysis was performed by counting the colony forming units. Reduction in colony count (RCC) between before and after the intervention in each group were compared using One-Way ANOVA. Results: The highest RCC was determined in NaOCl/PUI and the lowest in CHX/SNI (p<0.05). Regarding RCC, CHX/PUI showed statistically similar results with NaOCl/PUI and NaOCl/SNI (p>0.05). Conclusion: A PUI of 2% CHX induced a statistically similar amount of RCC with both a PUI of 2.5% NaOCl and SNI of 2.5 % NaOCl. PUI combined with 2 % CHX can be used in secondary endodontic infections and during routine endodontic treatment due to increased antibacterial efficiency against E. faecalis.
dc.identifier.doi10.4274/meandros.galenos.2020.55706
dc.identifier.endpage146
dc.identifier.issn2149-9063
dc.identifier.issue2
dc.identifier.startpage140
dc.identifier.trdizinid408996
dc.identifier.urihttps://doi.org/10.4274/meandros.galenos.2020.55706
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/408996
dc.identifier.urihttps://hdl.handle.net/20.500.14440/1029
dc.identifier.volume21
dc.identifier.wosWOS:000561738300008
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofMeandros Medical and Dental Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250201
dc.subjectAgitation
dc.subjectbiofilm
dc.subjectchlorhexidine
dc.subjectEnterococcus faecalis
dc.subjectpassive ultrasonic irrigation
dc.titleEvaluation of the Efficacy of 2% Chlorhexidine in Combination with Passive Ultrasonic Irrigation on Enterococcus faecalis Biofilm
dc.typeArticle

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