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Öğe Bioinspired synthesis of nanocomposites(IGI Global, 2024) Ekrikaya, Semiha; Danisman, Hikmetnur; Baktir, Seda; Arslan, Soley Arslan; Ocsoy, IsmailThe design of nanocoatings and nanostructured based surfaces stands out in many fields and biomedical applications due to their superior advantages over traditional coatings. With current nanotechnological approaches, properties such as antimicrobial activity, biocompatibility, increased product life-time, quality interface bonding, enhanced chemical and mechanical properties, high hardness, heat insulation, dirt and water repellency, corrosion resistance, improved energy efficiency, and reduced moisture absorption have been significantly improved. In recent years, the use of NPs and nanocoatings in the design and development of many dental materials has become highly popular in dentistry due to their ability to provide unique combinations of properties. This section will primarily focus on nanocoating materials used in dentistry. © 2024, IGI Global.Öğe Bruksizm Hakkında Bilgi Kaynağı Olarak YouTube™: Kesitsel İçerik Analizi(2023) Aygör, Fehime Alkan; Ekrikaya, SemihaAmaç: Bruksizm ile ilgili bilgi kaynağı olarak YouTube™ videolarının içeriğinin ve kalitelerinin değerlendirilmesidir. Gereç ve Yöntem: YouTube™ videolarında “diş sıkma, bruksizm” kelimeleri ile Türkçe videolarda arama yapıldı ve ilk sırada yer alan videoların URL’leri kaydedilerek iki araştırmacı tarafından tüm videolar incelendi. Videolara ait tanımlayıcı istatistikler kaydedildi ve verilerin minimum, maksimum, ortalama, standart sapması hesaplandı. Elde edilen değerler, istatistiksel olarak incelendi ve sürekli değişkenler Kruskal-Wallis testi ile analiz edildi (p<0.05). Bulgular: Toplam 250 video değerlendirmeye alındı. Bu videolardan değerlendirme kriterlerine uyan 68 video çalışmaya dahil edildi. Değerlendirmeyi yapan iki gözlemci arasında istatistiksel olarak anlamlı seviyede yeterli uyum vardı (Kappa=0.754, p<0.001). Videolar içerdikleri bilgi kalitesine göre değerlendirildiğinde, %10’u mükemmel, %56’sı iyi, %29’u zayıf ve %5’i kötü olarak skorlandı. Kruskal-Wallis testine göre video süresi ve yüklenme tarihinden itibaren geçen zamana göre istatistiksel fark tespit edildi. Ayrıca video kaynağı türü ile video tanımlayıcı istatistiklerinin kıyaslanması sonucu video süresi ve yüklenme tarihinden itibaren geçen zamana göre bazı parametrelerde istatistiksel fark tespit edildi. Ancak Bonferroni-Dunn testi kullanılarak yapılan çoklu karşılaştırma sonuçlarına göre istatistiksel olarak anlamlı farklılık yoktu (p>0.05). Sonuç: Bruksizm ile ilgili YouTube™’da yer alan videoların çoğu az yararlıdır. Alanında uzman hekimler ve akademisyenler, YouTube™’a daha yararlı ve bilgilendirici videolar ile katkı sağlayabilirler, bireylerin doğru bilgiye ulaşmasına ve toplum sağlığına faydalı olabilirler.Öğe Dental Çürük ile Mücadelede Antibakteriyel ve Remineralize Edici Etki İçin Nanoteknoloji Kullanımı(2023) Ekrikaya, Semiha; Demirbuğa, SezerDental çürükler günümüzdeki en yaygın kronik hastalıklardan biridir. Diş hekimliğinde nanoteknoloji ile biyofilm asitlerini kontrol ederek ve remineralizasyonu artırarak çürüğü önlemeyi amaçlayan çalışmalar yapılmaktadır. Nanoteknolojik yaklaşımlarla geliştirilen materyaller koruyucu diş hekimliği ve restoratif diş hekimliğinde başarılı bir şekilde kullanılabilmektedir. Güncel literatür çalışmalarında çeşitli monomerler ve metal nanopartiküllerinin antibakteriyel ve remineralizasyon kapasiteleri ile ilgili çeşitli araştırmalar yapılmıştır. Yapılan çalışmalarda çeşitli monomerler ve nanopartiküllerin remineralize edici ve antibakteriyel etkinliği kanıtlanmıştır. Bu monomerler ve nanopartiküller dental kompozitler, simanlar, örtücüler, kaideler ve adezivler içerisine dahil edilerek antibakteriyel etkinlik ve remineralizasyon sağlamak için umut vericidir. Bu nedenlerle nanoteknoloji, koruyucu ve restoratif diş hekimliğini önemli ölçüde geliştirme potansiyeline sahiptir. Ancak nanoteknoloji ürünlerinin muhtemel toksisitesi ve dezavantajları ile ilgili bilgi sınırlıdır. Dental materyaller üzerinde nanopartiküllerin uzun süreli antimikrobiyal, toksik, fiziksel ve klinik etkileri daha ileri çalışmalarda araştırılması gerekir.Öğe Dentin bond strength and antimicrobial activities of universal adhesives containing silver nanoparticles synthesized with Rosa canina extract(Springer Heidelberg, 2023) Ekrikaya, Semiha; Yilmaz, Ebubekir; Arslan, Soley; Karaaslan, Rabia; Ildiz, Nilay; Celik, Cagla; Ocsoy, IsmailObjective The purpose in the study was to evaluate the effect of biogenic silver nanoparticles (Ag NPs) synthesized by the green synthesis method on dentin bond strength in three different universal adhesives and investigate their antibiofilm activity against Streptococcus mutans (S. mutans).Materials and methods Three different universal adhesives (single bond universal, all-bond universal, and clearfil universal) were used in this study. Ag NPs were synthesized using rose hip (Rosa canina) extract as a reducing and stabilizing agent and they were characterized with STEM, UV-vis spectrophotometer, DLS, and zeta potential. Ag NPs were added to the adhesive resins at a rate of 0.05% (w/w), and their homogeneous distribution in the adhesive was determined using EDX spectrometry. Samples in all groups were tested at baseline-after 5000 and 10,000 thermal cycles. Adhesive composite discs were used for the live/dead analysis of S. mutans, MTT metabolic activity test, lactic acid production, and determination of colony-forming unit (CFU) values (n = 3). Ninety extracted caries-free human third molars were used to determine microtensile bond strength (mu TBS) (n = 10). After the universal adhesive was applied to the dentin surface, composite resin (Z550 XT, 3 M ESPE, USA) was placed and sections were taken to form a composite-dentin stick of 1 mm x 1 mm wideness and 8-mm length. The sticks were broken at a rate of 1 mm/min under uniaxial tension in a universal testing machine, and the failure modes were determined by SEM. One-way analysis of variance (ANOVA) for antibacterial tests and two-way analysis of variance for mu TBS tests were performed (p < 0.05).Results All universal adhesive groups containing Ag NPs showed higher antibacterial activity than control groups without Ag NPs (p < 0.05). There was a statistically significant difference in the live/dead assay analysis, MTT metabolic activity test, lactic acid production, and CFU values in the thermal cycled Ag NPs groups (p < 0.05). Antibacterial activity decreased in groups containing Ag NPs subjected to 10,000 thermal cycles. The highest lactic acid production 11.06 (+/- 0.629) and CFUs 7.61 (+/- 0.304), live bacteria 31.13 (+/- 0.466), and S. mutans MTT metabolic activity 0.29 (+/- 0.376) at AU (All-Bond Universal-Ag NPs) 10,000 thermal cycles group. There was no difference in mu TBS values between the initial and 5000 thermal cycle groups, there was a difference between the 10,000 thermal cycle groups. The CU (Clearfil Universal-Ag NPs) group subjected to 10,000 thermal cycles showed lower mu TBS 11.1 (+/- 3.2).Conclusion In conclusion, universal adhesives containing biogenic Ag NPs showed higher antibacterial activity than the control groups and did not reduce the mu TBS.Öğe DTMOS tekniğini kullanarak 0.2V besleme gerilimli ve %97 enerji verimli özel-veya lojik kapı tasarımları(2022) Emir, Recep; Ekrikaya, Semiha; Demirbuğa, Sezer; Avcı, BurhanettinBu çalışmada, Dynamic Threshold-voltage MOSFET (DTMOS) tekniğini kullanarak aşırı düşük besleme gerilimli ve enerji verimli ÖZEL-VEYA lojik kapıları önerilmektedir. Birçok alanda tasarım tekniği olarak kullanılan ancak lojik kapı devresi tasarımında yeterince uygulanmamış DTMOS tekniği tasarım yöntemi olarak bu çalışmada kullanılmaktadır. Önerilen lojik kapıların amacı transistör kanal parametrelerini değiştirmeden DTMOS tekniğini kullanarak besleme gerilimini ve harcanan gücü azaltmaktır. 0.2V besleme geriliminde ve 1GHz çalışma frekansında incelenen üç farklı ÖZEL-VEYA lojik kapısı arasında DTMOS transistörlü tasarımlarda güç tüketimi en düşük 0.228nW değerindedir. Üç lojik kapıda da DTMOS tekniği %97 oranında enerji verimliliği sağlamaktadır. Teorik sonuçlar CMOS 65nm teknolojisini kullanan HSPICE programında doğrulanmıştır. Elde edilen sonuçlar düşük gerilim ve enerji verimliliği gerektiren uygulamalarda DTMOS tekniğinin etkili bir yöntem olduğunu göstermektedir.Öğe Effect of Different Beverages and Polishing Systems on Color Stability and Surface Roughness of a Smart Chromatic Composite Resin and Methacrylate Composites(Ataturk University, 2025) Ekrikaya, Semiha; Karataş, ÖzcanObjective: The purpose of the study is to evaluate the color stability and surface roughness of smart chromatic composite resin and methacrylate composite resins with applying different polishing systems and stored in different solutions. Methods: In the study, 120 disc-shaped specimens were prepared from a smart chromatic composite, a nanofill composite, and a nanohybrid composite. The specimens were separated into 12 groups with a specimen size of 10, and the two different polishing systems were utilized. The initial color values of the specimens were measured with a spectrophotometer and the surface roughness values were measured with a profilometer. Then, the specimens were stored in two different beverage solutions, and color and roughness measurements were repeated. The mean color change values of the specimens were calculated in ?E, and the surface roughness values were recorded in Ra. Statistical analysis of the data was performed using One-way ANOVA and post hoc Tukey test (P =.05). Results: Statistically significant variations were observed in the mean color change values among the groups, as a consequence of the utilization of various polishing systems and exposure to different solutions (P.05). Although no significant variations were observed in the mean surface roughness values of the specimens due to exposure to different solutions (P >.05), significant distinctions were identified among the groups to which different polishing systems were employed (P <.05). Conclusion: The application of different polishing systems and exposure to various solutions can result in variations in color and surface roughness values for composite resins, owing to their inherent structural characteristics. Keywords: Color Change, Composite Resin, Profilometer, Smart Chromatic Composite, Surface RoughnessÖğe Effect of Various Surface Treatments Applied on Glass Fiber Post and Universal Adhesives on Microtensile Bond Strength and Investigation of Surface Properties with EDX(Korean Fiber Soc, 2023) Ekrikaya, Semiha; Demirbuğa, Sezer; Kilinc, Nazire Nurdan Cakir; Avci, BurhanettinThe purpose of this study is to investigate the effects of various surface treatments and universal adhesives on the changes in the glass fiber posts (GFPs) surface and the bond strength between resin cement-post and core composite-post. A total of 20 groups (n = 16) were formed, 10 groups for resin cement and 10 groups for core composite. Various surface treatments, including acid etching and silane application, and two different universal adhesives (Single bond Universal, All Bond Universal) were applied. After various surface treatments and adhesives were applied to the GFPs surface, the surface properties were examined by energy-dispersive X-ray spectroscopy (EDX) analysis. Standard silicone molds were prepared to bond the resin cement and core composite with the GFPs. The serial 1 mm thickness bar was taken from each sample. Microtensile bond strength (& mu;TBS) test was performed and failure modes were evaluated by scanning electron microscopy (SEM). Statistical analysis was performed using a two-way analysis of variance and Tukey's post hoc tests (p = 0.05). The bond strength values of the groups that applied 37% orthophosphoric acid (OPA), silane, and universal adhesive to the GFPs surface before the resin cement and core composite were statistically significantly higher than the control group (p < 0.05). In the resin cement study, the group using silane and Single Bond Universal showed higher bond strength than the other groups (p < 0.05). Acid etching and silane application before the use of universal adhesives increased the & mu;TBS in both resin cement and core composite groups.Öğe Evaluation of the antibacterial activity of dental adhesive containing biogenic silver nanoparticles decorated nanographene oxide nanocomposites (Ag@nGO NCs) and effect on bond strength to dentine(Springer, 2024) Arslan, Soley; Ekrikaya, Semiha; Ildiz, Nilay; Yusufbeyoglu, Sadi; Ocsoy, IsmailOur study aimed to evaluate the antibacterial activities and dentin bond strengths of silver nanoparticles (Ag NPs) and silver nano-graphene oxide nanocomposites (Ag@nGO NCs) produced by green and chemical synthesis methods added to the dental adhesive. Ag NPs were produced by green synthesis (biogenic) (B-Ag NPs) and chemical synthesis methods (C-Ag NPs) and deposited on nGO (nano-graphene oxide). Ag NPs and Ag@nGO NCs (0.05% w/w) were added to the primer and bond (Clearfil SE Bond). Group 1: control, Group 2: nGO, Group 3: B-Ag NPs, Group 4: B-Ag@nGO NCs, Group 5: C-Ag NPs, Group 6: C-Ag@nGO NCs. Streptococcus mutans (S. mutans) live/dead assay analysis, MTT metabolic activity test, agar disc diffusion test, lactic acid production, and colony forming units (CFUs) tests were performed. Bond strength values were determined by the microtensile bond strength test (& mu;TBS). Failure types were determined by evaluating with SEM. Statistical analysis was performed using one-way ANOVA and two-way ANOVA (p < 0.05). There was a difference between the groups in the viable bacteria ratio and lactic acid production tests (p < 0.05). When the inhibition zone and S. mutans CFUs were evaluated, there was no difference between Group 3 and Group 4 (p > 0.05), but there was a difference between the other groups (p < 0.05). When the metabolic activity of S. mutans was evaluated, there was a difference between Group 1 and other groups, and between Group 2 and Group 5, and Group 6 (p < 0.05). There was no difference between the groups in the & mu;TBS values (p > 0.05). As a result, although the antibacterial activity of B-Ag NPs and B-Ag@nGO Ag NPs obtained by green synthesis is lower than that of chemically synthesis obtained C-Ag NPs and C-Ag@nGO NCs, they provided higher antibacterial activity compared to the control group and did not reduce & mu;TBS. The addition of biogenic Ag NPs to the adhesive system increased the antibacterial effect by maintaining the bond strength of the adhesive. Antibacterial adhesives can increase the restoration life by protecting the tooth-adhesive interface.Öğe Güncel Diş Hekimliğinde Fiber Kullanımı ve Fiberle Güçlendirilmiş Restorasyonlar(Akademisyen Yayınevi, 2022) Ekrikaya, SemihaFiberler birçok biyomedikal alanda olduğu gibi yaklaşık 25 yıldır diş hekimliği uygulamalarında da kullanılmaktadır (1). Fiberlerin temel görevi materyaller içe risinde kuvvet kırıcı olarak görev yaparak materyalin mekanik ve fiziksel özel liklerini arttırmaktır (2). Fiberler diş hekimliğinde ilk kez polimetil metakrilatın mekanik özelliklerini geliştirmek ve boyutsal stabilitesini artırmak için kullanıl mıştır (3). Diş hekimliğindeki gelişmeler ve hastaların estetik algılarının değişmesi so nucunda restoratif tedavilerde kompozit materyallerin kullanımı yaygınlaşmıştır. Ancak yüksek strese maruz kalan bölgelerde kompozit restorasyonların mekanik özellikleri ve kullanım endikasyonları sınırlı kalabilmektedir. Bu nedenle kom pozit rezinlerin fiberle güçlendirilmesi gündeme gelmiş ve bu konuda çalışmalar yapılmıştır (4). Fiberle güçlendirilmiş kompozitler ve kompozit restorasyon ya pımında fiber yapılı materyallerin kullanımı güncel tedavilerde yaygınlaşmakta dır (4). Fiberler; düşük elastik modül, yüksek basma mukavemeti, üstün estetik özellikler ve rezin materyaller ile adeziv bağlanabilme gibi avantajlara sahiptir. Bununla birlikte stres kırıcı ve dağıtıcı özellikleri ile restoratif materyallerin 1me kanik özelliklerini arttırır. Fiberle güçlendirilmiş kompozit restorasyonlar gele neksel restoratif materyallere göre diş dokusunu daha iyi taklit edebilmekte ve daha güçlü mekanik özellikler sergilemektedir (5). Fiber yapılar kompozit res torasyonlar içerisinde stres kırıcı olarak görev yapmakta ve mekanik kuvvet ile timini azaltarak restorasyon başarısını artırmaktadır (1). Bu özellikleri ile resto ratif diş hekimliğinde direkt kompozit restorasyonlarda, post-core yapımında ve CAD\CAM restorasyonlarla kullanılabilirler. Ayrıca çeşitli örgü fiberler ile adeziv köprü yapımı, splint görevi ve restorasyonların mekanik özelliklerinin artırılması sağlanabilir (6, 7).Öğe The effect of two different prophylaxis paste applying processes on color stability in-office bleaching: 24-month clinical follow-up(Springer Heidelberg, 2022) Ekrikaya, Semiha; Demirbuğa, SezerObjective The purpose of this study was to examine the effect of applying two different prophylaxis pastes with various protocols on the degree of bleaching and color stability in the office bleaching process with a bleaching agent containing 40% hydrogen peroxide. Material and method The 300 teeth of 15 (9 female, 6 male) patients were included in our study, and 5 different study groups were randomly formed. The bleaching process with Ultradent Opalescence Boost (Ultradent, South Jordan, USA) was performed according to the manufacturer's instructions. Two different prophylaxis pastes, Ultrapro (Ultradent, Cologne, Germany) and Cleanic (Kerr, Rastatt, Germany), were applied with protocols determined according to the groups. The effect on color stability at 6-, 12-, and 24-month follow-up was determined using the CIE L* a* b* color system. The changes in the parameters were analyzed using the one-way ANOVA, chi-square, and Tukey test (p > 0.05). Results The evaluation rate of the treatments was 100% at the end of 24 months. Control group 6-month Delta E (0-6) and 12-month Delta E (0-12) values were higher than 24-month Delta E (0-12) values. UU + UU, KC + KC, and UU group 6-month Delta E (0-6) values were higher than 12-month Delta E (0-12) values. In addition, 6-month Delta E (0-6) and 12-month Delta E (0-12) values were higher than 24-month Delta E (0-24) values. KC group 6-month Delta E (0-6) and 12-month Delta E (0-12) values were higher than 24-month Delta E (0-24) values. Control, UU + UU, KC + KC, UU, and KC group Delta E (1-6) values at 6 months were lower than 12-month Delta E (1-12) and 24-month Delta E (1-12) values in all groups. In addition, 12-month Delta E (1-12) values were lower than 24-month Delta E (1-24) values. According to the study data, there was no statistically significant difference between the groups according to the prophylaxis paste and prophylaxis procedure (p > 0.05). However, it was observed that whiteness decreased in all groups over time. Conclusions Discoloration was observed at 6 months, 12 months, and 24 months after bleaching. However, at the end of 24 months, the tooth color was significantly whiter than the initial color.