This study aimed to measure total aflatoxin (AF) (AFB1, AFB2, AFG1, and AFG2) and ochratoxin A (OTA) levels in dried fruit samples and to evaluate the potential dietary exposure and cancer risk to these mycotoxins in Kayseri/Türkiye. Dried fruit samples were collected between April–May 2021. A total of 11 dried grapes and apricot samples, 7 dried fig and plum samples were collected. Total aflatoxins and OTA in dried fruits were determined by ELISA method. Then, the margin of exposure (MOE) and cancer risk were calculated. Total AF was detected in dried fruit samples between 42.86%, and 100%. Between 18.18% and 57.14% of samples exceeded the European Commission (EC) limits for total AF. Moreover, OTA was detected in all samples. Between 71.43% and 100% of samples exceeded the EC limits for OTA. Cancer risk due to OTA exposure was higher than total AF and it was determined that OTA exposure could pose a risk for public health (MOE <10,000). Although mycotoxin exposure seems to be low due to the low consumption of dried fruit in Türkiye, the risk of exposure and cancer may increase because of complying with the recommendations of the dietary guidelines. The findings provide new insights into exposure to total AF and OTA through the consumption of dried fruit.
Eser Adı (dc.title) | Total aflatoxin and ochratoxin A levels, dietary exposure and cancer risk assessment in dried fruits in Türkiye |
Yazar (dc.contributor.author) | Gizem Aytekin Şahin |
Yazar (dc.contributor.author) | Yusuf AYKEMAT |
Yazar (dc.contributor.author) | Ayşegül Tuğba YILDIZ |
Yazar (dc.contributor.author) | Neriman İNANÇ |
Tür (dc.type) | Makale/Derleme |
Dizin Platformu (dc.relation.platform) | Diğer |
Tarih (dc.date.issued) | 2024 |
WOS Kategorileri (dc.identifier.wos) | SCI SCI Eaxp AHCI Indeksleri |
Makalenin Sayısı (dc.identifier.issue) | 237 |
Cilt Numarası (dc.identifier.volume) | 2024 |
Yayıncı (dc.publisher) | Elsevier |
Yayının Son Sayfa Sayısı (dc.identifier.endpage) | 6 |
Yayının İlk Sayfa Sayısı (dc.identifier.startpage) | 1 |
DOI Numarası (dc.identifier.doi) | https://doi.org/10.1016/j.toxicon.2023.107540 |
ORCID No (dc.contributor.orcid) | 0000-0002-6620-9259 |
Dil (dc.language.iso) | İngilizce |
Tam Metin Yayınlansın Mı? (dc.identifier.tammetin) | Hayır |
Özet (dc.description.abstract) | This study aimed to measure total aflatoxin (AF) (AFB1, AFB2, AFG1, and AFG2) and ochratoxin A (OTA) levels in dried fruit samples and to evaluate the potential dietary exposure and cancer risk to these mycotoxins in Kayseri/Türkiye. Dried fruit samples were collected between April–May 2021. A total of 11 dried grapes and apricot samples, 7 dried fig and plum samples were collected. Total aflatoxins and OTA in dried fruits were determined by ELISA method. Then, the margin of exposure (MOE) and cancer risk were calculated. Total AF was detected in dried fruit samples between 42.86%, and 100%. Between 18.18% and 57.14% of samples exceeded the European Commission (EC) limits for total AF. Moreover, OTA was detected in all samples. Between 71.43% and 100% of samples exceeded the EC limits for OTA. Cancer risk due to OTA exposure was higher than total AF and it was determined that OTA exposure could pose a risk for public health (MOE <10,000). Although mycotoxin exposure seems to be low due to the low consumption of dried fruit in Türkiye, the risk of exposure and cancer may increase because of complying with the recommendations of the dietary guidelines. The findings provide new insights into exposure to total AF and OTA through the consumption of dried fruit. |
İsmi Geçen (dc.identifier.ismigecen) | Üniversite ismi geçen |
Açık Erişim Tarihi (dc.date.available) | 2024-01-11 |
Konu Başlıkları (dc.subject) | Beslenme ve Diyetetik |
Dergi, konferans, armağan kitap adı (dc.relation.journal) | Toxicon |