Evaluation of the antibacterial activity of dental adhesive containing biogenic silver nanoparticles decorated nanographene oxide nanocomposites (Ag@nGO NCs) and effect on bond strength to dentine

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dc.authoridEkrikaya, Semiha/0000-0003-1970-0421
dc.contributor.authorArslan, Soley
dc.contributor.authorEkrikaya, Semiha
dc.contributor.authorIldiz, Nilay
dc.contributor.authorYusufbeyoglu, Sadi
dc.contributor.authorOcsoy, Ismail
dc.date.accessioned2025-02-24T17:18:54Z
dc.date.available2025-02-24T17:18:54Z
dc.date.issued2024
dc.departmentFakülteler, Diş Hekimliği Fakültesi, Restoratif Diş Tedavisi Ana Bilim Dalı
dc.description.abstractOur study aimed to evaluate the antibacterial activities and dentin bond strengths of silver nanoparticles (Ag NPs) and silver nano-graphene oxide nanocomposites (Ag@nGO NCs) produced by green and chemical synthesis methods added to the dental adhesive. Ag NPs were produced by green synthesis (biogenic) (B-Ag NPs) and chemical synthesis methods (C-Ag NPs) and deposited on nGO (nano-graphene oxide). Ag NPs and Ag@nGO NCs (0.05% w/w) were added to the primer and bond (Clearfil SE Bond). Group 1: control, Group 2: nGO, Group 3: B-Ag NPs, Group 4: B-Ag@nGO NCs, Group 5: C-Ag NPs, Group 6: C-Ag@nGO NCs. Streptococcus mutans (S. mutans) live/dead assay analysis, MTT metabolic activity test, agar disc diffusion test, lactic acid production, and colony forming units (CFUs) tests were performed. Bond strength values were determined by the microtensile bond strength test (& mu;TBS). Failure types were determined by evaluating with SEM. Statistical analysis was performed using one-way ANOVA and two-way ANOVA (p < 0.05). There was a difference between the groups in the viable bacteria ratio and lactic acid production tests (p < 0.05). When the inhibition zone and S. mutans CFUs were evaluated, there was no difference between Group 3 and Group 4 (p > 0.05), but there was a difference between the other groups (p < 0.05). When the metabolic activity of S. mutans was evaluated, there was a difference between Group 1 and other groups, and between Group 2 and Group 5, and Group 6 (p < 0.05). There was no difference between the groups in the & mu;TBS values (p > 0.05). As a result, although the antibacterial activity of B-Ag NPs and B-Ag@nGO Ag NPs obtained by green synthesis is lower than that of chemically synthesis obtained C-Ag NPs and C-Ag@nGO NCs, they provided higher antibacterial activity compared to the control group and did not reduce & mu;TBS. The addition of biogenic Ag NPs to the adhesive system increased the antibacterial effect by maintaining the bond strength of the adhesive. Antibacterial adhesives can increase the restoration life by protecting the tooth-adhesive interface.
dc.description.sponsorshipTechnological and Scientific Council of Turkey (TUBITAK) [220S445]
dc.description.sponsorshipThis study was funded by the Technological and Scientific Council of Turkey (TUBITAK) (Project number: 220S445)
dc.identifier.doi10.1007/s10266-023-00836-7
dc.identifier.endpage354
dc.identifier.issn1618-1247
dc.identifier.issn1618-1255
dc.identifier.issue2
dc.identifier.pmid37436660
dc.identifier.scopus2-s2.0-85164464293
dc.identifier.scopusqualityQ1
dc.identifier.startpage341
dc.identifier.urihttps://doi.org/10.1007/s10266-023-00836-7
dc.identifier.urihttps://hdl.handle.net/20.500.14440/910
dc.identifier.volume112
dc.identifier.wosWOS:001026718200001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofOdontology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250201
dc.subjectAntibacterial activity
dc.subjectBiogenic Ag NPs
dc.subjectBiogenic Ag@nGO NCs
dc.subjectBond strength
dc.subjectDental adhesive
dc.titleEvaluation of the antibacterial activity of dental adhesive containing biogenic silver nanoparticles decorated nanographene oxide nanocomposites (Ag@nGO NCs) and effect on bond strength to dentine
dc.typeArticle

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