Yazar "Aslan, Gönül" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • [ X ]
    Öğe
    Molecular detection of E. faecalis in oral samples of a population associated with secondary endodontic infection
    (2021) Kesim, Bertan; Ülger, Seda Tezcan; Cudal, Hamza; Aslan, Gönül; Ersoy, Leyla; Arslan, Tuğrul; Küçük, Mustafa Öner
    Aim: The objective of this study was to evaluate the prevalence of\rEnterococcus faecalis in samples of oral rinse and tongue dorsum of\rendodontic patients with secondary/persistent infections (EPSI) using the\rPCR method.\rMethodology: Oral rinse samples (ORS) and tongue swab samples (TSS)\rof 22 patients (EPSI group) and 32 healthy individuals (control group) were\rcollected. DNA isolation from the TSS and ORS samples was performed\rusing the modified classical phenol-chloroform and chloroform method. To\rdetect E. faecalis strains directly from the TSS and ORS samples, the 310\rbase pair (bp) segment of the 16S rDNA of the E. faecalis genome was\ramplified by PCR using specific primers. The prevalence of E. faecalis was\rcompared between healthy and sick individuals using the Chi-square test,\rsignificance was set at p<0.05.\rResults: In the ORS samples, there was a significant difference between\rthe healthy individuals (n = 11, 34%) and the EPSI group (n = 15, 68%) in\rterms of the presence of E. faecalis (p = 0.026). In the TSS, the presence\rof E. faecalis was also investigated, and a significant difference was found\rbetween healthy individuals (n = 3, 9%) and the EPSI group (n = 11, 50%) (p\r= 0.001). In the EPSI group, no statistically significant difference was\rpresent in the prevalence rate of E. faecalis between the samples of ORS\r(68%) and TSS (50%) (p = 0.358).\rConclusion: The prevalence of E. faecalis was found to be statistically\rsignificantly higher in multi-site oral samples of a population with\rsecondary endodontic infection than healthy individuals.
  • [ X ]
    Öğe
    Technology development and digital transformation conflicts
    (2022) Oralhan, Burcu; Ülger, Seda Tezcan; Aslan, Gönül
    Today, businesses, organizations and governments attach great importance to digital transformation to meet the needs of their customers, business partners, and employees to adapt to the developing technology in recent years. Digital transformation, which is a challenging and mandatory process, has been and continues to be passed by institutions today. However, the successful management of this transformation without conflict can be realized by accurately detecting new communication technologies and examining, understanding, and implementing the transformation process in detail. This process will be painful, where radical changes will take place in the structure, processes, functions, and business models of the organization. Different challenges may be encountered in each of the startup, execution, and governance subprocesses examined in the digital transformation process. Many conflicts such as time and budget shortages, inadequate digital skills and lack of vision for digital customer processes, cybersecurity threats, human resource shortages, difficulty in managing technology, failure to achieve cloud structure integration, vision, and culture differences are the reasons why this process cannot be managed fluently and accurately. For businesses that focus on this goal, regardless of scale, digital transformation has become a necessity, not an alternative to choose. In this study, the digital transformation process and maturity model were discussed, and technological and digital conflicts were emphasized. It seeks to shed light on the work they will do by making recommendations for institutions to manage this process in the best way.