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Amplicon‑based next‑generation sequencing for comparative analysis of root canal microbiome of teeth with primary and persistent/ secondary endodontic infections

Bertan KESİM | Mustafa Öner KÜÇÜK

Abstract Objectives To compare the root canal microbiome profiles of primary and persistent/secondary infections using highthroughput sequencing with the help of a reliable bioinformatics algorithm. Materials and methods Root canal samples of 10 teeth in the primary endodontic infection (PEI) group and 10 teeth in the persistent/secondary endodontic infection (SEI) group were included resulting in a total of 20 samples. After DNA extraction from the samples, sequencing was performed on the Illumina MiSeq platform. Pair-end Illumina reads were imported to QIIME 2; amplicon sequence variants (AS ...Daha fazlası

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Prevalence of persistent apical periodontitis in patients with root canal-filled teeth: A cone-beam computed tomography study

Bertan KESİM

Abstract Aim: Apical periodontitis is the inflammatory destruction of periradicular tissues that occurs gradually over time, primarily originating from invading bacteria in the root canal system and initiated by the release of bacterial products. In this study, the prevalence of post-treatment apical periodontitis was assessed with cone-beam computed tomography imaging and the effects of tooth-level and patient-level factors that may predict the failure of root canal treatment were investigated in a Turkish subpopulation. Material and Methods: Our study included 305 cone-beam computed tomograp ...Daha fazlası

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Registered Replication Report: Study 1 From Finkel, Rusbult, Kumashiro, & Hannon (2002)

Bülent AYKUTOĞLU

Finkel, Rusbult, Kumashiro, and Hannon (2002, Study 1) demonstrated a causal link between subjective commitment to a relationship and how people responded to hypothetical betrayals of that relationship. Participants primed to think about their commitment to their partner (high commitment) reacted to the betrayals with reduced exit and neglect responses relative to those primed to think about their independence from their partner (low commitment). The priming manipulation did not affect constructive voice and loyalty responses. Although other studies have demonstrated a correlation between subj ...Daha fazlası

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Basic psychological need frustration and health: Prospective associations with sleep quality and cholesterol

Bülent AYKUTOĞLU

In the present study we examined whether basic psychological need frustration is related to poor sleep quality and risky cholesterol levels using National Survey of Midlife Development in the United States (MIDUS) data sets. We first constructed autonomy, competence and relatedness frustration scales from the items used in the MIDUS survey and validated its factor structure in a pilot study (N = 287). An exploratory factor analysis showed that the selected items loaded on to the respective need frustration subscales of basic psychological need satisfaction and frustration scale. Next, a confir ...Daha fazlası

6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.
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