Rhamnetin improves antioxidant status in the liver of Ehrlich solid tumor bearing mice

Neriman İNANÇ | Mustafa NİSARİ

Objective:Rhamnetin, a flavanol, is in the subclasses of the flavonoids existing in plants. The antioxidant properties of several plants containing flavonoids have been extensively studied in several diseases including cancer. This study investigated the effects of rhamnetin on tumor masses, oxidant and antioxidant status in the livers of mice bearing Ehrlich solid tumor. Material and Methods:Fifty male Balb/C mice weighing 25-30 g were used in the study. Ten mice were keptfor Ehrlich ascites tumor (EAT) cells production and the remaining mice were randomly assigned to four groups containing 1 ...Daha fazlası

Makale/Derleme 2020 Medical Science and Discovery 16 Görüntülenme

Effects of fenugreek extract on total antioxidant/oxidant status at ehrlich ascites tumor bearing mice, ejmı

Neriman İNANÇ | Mustafa NİSARİ

Cancer is the second most common cause of death in the world. Several natural products have been studied for anticancer activity and for the prevention or repair of oxidative injury. Curcumin is one of the natural products of high medicinal interest. This study was performed to investigate the effects of curcumin on lipid peroxidation and antioxidant enzymes in tissues of mice bearing Ehrlich solid tumor. Forty mice were distributed to four groups as healthy control and treatments that received 1x106 Ehrlich ascites tumor (EAT) cells and EAT cells plus 25 mg/kg/day or 50 mg/kg/day curcumin wit ...Daha fazlası

Makale/Derleme 2020 Advances in Hygiene and Experimental Medicine 10 Görüntülenme

Bir deneysel iskemi/reperfüzyon modelinde serbest radikal yakalayısı olarak Urtica diocia

Neriman İNANÇ | Mustafa NİSARİ

Bildiri

Bildiri 2020 Kayseri, 2020 10 Görüntülenme

Uric acid-lymphocyte ratios and myocardial damage parameters in ST elevated myocardial infarction

Mustafa NİSARİ

Aim: Major negative cardiovascular outcomes and uric acid (UA), neutrophil: lymphocyte ratio (NLR) and lymphocyte levels have been demonstrated in up-to-date studies. In this study, it was aimed to investigate ULAR in patients with STEMI and unstable angina pectoris (UAP) who underwent primary percutaneous coronary intervention. For this purpose, we evaluated relationships between UALR and markers of myocardial injury (troponin I, creatine kinaseMB) inflammatory markers (high-sensitivity C-reactive protein [hsCRP]) and blood count parameters), serum lipids and myocardial contractility. Materia ...Daha fazlası

Makale/Derleme 2020 J Contemp Med 8 Görüntülenme

Effects of MTHFR C677T gene polymorphism on migraine together with biochemical and clinical parameters in Turkish population

Mustafa NİSARİ

o detect the relation between methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism and both of clinical and biochemical parameters. One hundred sixty migraine patients and one hundred twenty control group were included in the current study. Pain intensity of individuals were measured, biochemical, clinical parameters and MTHFR C677T single nucleotide polymorphism were detected. Statistically higher occurrence MTHFR C677T genotype was detected in migraine group than control group. A statistically significant association between family history of migraine and MTHFR C677T genotypes ...Daha fazlası

Makale/Derleme 2020 Progress in Nutrition 4 Görüntülenme

Biochemical effects of caffeine and melatonin on rat embryo brain

Mustafa NİSARİ

Background:Oxidative stress plays an important role in fetus brain development. The aim of this study was to investigate the protective role of melatonin against the effect of caffeine (given 30 mg/kg and 60 mg/kg) in embryo brain.Material and Methods:For this purpose, 35 adult female Sprague-Dawley rats were used in the study. Pregnant rats were detected by vaginal smear test and were divided into seven groups with five rats per group.Thirty(30) mg/kg and 60 mg/kg caffeine were administered to the experimental groups between the 1st and 20th days of pregnancy, while melatonin (10 mg/kg) was a ...Daha fazlası

Makale/Derleme 2020 Journal of US-China Medical Science 10 Görüntülenme