Nuh Naci Yazgan Üniversitesi Kurumsal Akademik Arşivi
DSpace@NNY, Nuh Naci Yazgan Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Does cultural structure affect sexuality and marital adjustment in infertil women?
(Taylor & Francis, 2025) Bayraktar, Evrim; Kaya Erten, Zeliha; Uludağ, Zeki Semih
The place of infertility and infertility in culture is an important factor affecting the sexual and marital adjustment of individuals. The study aimed to examine how cultural structure affects sexuality and marital adjustment in infertile women with mixed methods. The quantitative part of the study was completed with 178 infertile women and in-depth interviews were conducted with 6 women in the qualitative part. Quantitative data were collected with the Patient Information Form, DAS and SQOL-F, MSPSS and qualitative data were collected with the in-depth interview form. There was a significant relationship between the years of marriage and the duration of infertility and the scale scores. In addition, infertile women stated that the cultural structure and the environment they lived in had a great impact on them. Health professionals should counsel individuals in improving the quality of life based on infertility and infertility-related problems and in resolving intra-family communication and sexual problems that significantly impair marital relationships.
Health-Related Quality of Life and Metabolic Control in Children and Adolescents with Type 1 Diabetes Mellitus
(Galenos Publ House, 2016) Caferoglu, Zeynep; İnanç, Neriman; Hatipoglu, Nihal; Kurtoglu, Selim
Objective: The burdens imposed on a child and his/her parents by a diagnosis of type 1 diabetes mellitus (T1DM) adversely affect their health-related quality of life (HRQoL). HRQoL is important for prognosis and is related to metabolic control. To evaluate the HRQoL of Turkish children and adolescents with T1DM and to assess the correlation of HRQoL subscales (including physical and psychosocial health) with metabolic control, and particularly with hypo-and hyperglycaemic episodes. Methods: This cross-sectional study included 70 participants with T1DM aged between 8 and 18 years (study group) and 72 healthy controls who were matched to the study group in terms of age, gender, and sociodemographic characteristics (control group), and their parents. HRQoL was determined by the Pediatric Quality of Life Inventory. As an indicator of metabolic control, the most recent hemoglobin A1c (HbA1c) levels were obtained and the number of hypo-and hyperglycaemic episodes over the past one month were checked. Results: The study group had similar HRQoL scores for children's self-reports to the control group apart from a decreasing psychosocial health score for parents' proxy-reports in the study group. Although HbA1c level was not related to HRQoL scores, lower number of hypo-and hyperglycaemic episodes were associated with an increase in psychosocial health scores and physical health scores as well as an increase in the total score for parents' proxy-reports. Conclusion: Although there was no correlation between metabolic control and HRQoL in children's self-reports, the improving HRQoL levels in parents' proxy-reports were associated with good metabolic control.
Correlation between the expressions of leptin and its receptors (ObR, sObR) in gastric cancer
(Walter De Gruyter Gmbh, 2016) Cakir, Isil; Kilic, Eser; Coskun, Banu Demet Ozel; Cakir, Nuri; Savaşçıhabeş, Asuman
Objective: The expressions of leptin and its receptor (ObR) have been observed in human gastric cancer (GC) tissue. Leptin can promote the proliferation of GC cells. However, the correlation between leptin and ObR expressions in GC and the role of gastric ObR protein levels in patients with GC is still unclear. This study aimed to evaluate the relationship between leptin, gastric ObR protein and soluble leptin receptor (sObR) levels and whether their possible role of indicator in GC. Methods: Serum leptin, gastric leptin and serum sObR concentrations were determined in 30 male patients with GC and 25 male dyspeptic subjects by enzyme linked immunosorbent assay. We analysed the expression of gastric ObR levels in endoscopically obtained biopsy samples by using Western Blotting method. Results: Compared with controls, patients had lower serum leptin and higher gastric tissue leptin levels. sObR protein concentrations of patients were detected significantly higher, gastric ObR protein expression were lower than subjects in control group. Conclusion: Leptin in gastric cancerous region and sObR in circulation are overexpressed in GC. Their expressions are associated with malignancy. Decreased leptin levels, induces the sObR signal in circulation. This negative feedback regulation is also seen in gastric tissue: increased gastric tissue leptin levels inhibits gastric ObR protein expression. Thus, leptin and ObR may be important indicators in GC.
Alexithymia levels in patients with unipolar and bipolar depression and the effect of alexithymia on both severity of depression symptoms and quality of life
(Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2016) Karayagiz, Saban; Basturk, Mustafa
Objective: Aims of this study are to compare the alexithymia scores of patients with unipolar depression (UD), bipolar affective disorder depressive episode (BAD-D) and healthy controls, to explore the effects of alexithymia scores on both severity of depression symptoms and quality of life. Methods: Case group of the study is consisted of one hundred and eighteen UD diagnosed, forty eight BAD-depression diagnosed patients, based on DSM-IV-TR criteria. Control group of the study is consisted of ninety six people who had no history of psychiatric disease. Overall, 262 people had involved in the study. Sociodemographic and Clinical Data Form, Hamilton Rating Scale for Depression (HRDS), Beck Depression Inventory (BDI), Toronto Alexithymia Scale (TAS-20) and SF-36 Quality of Life Scale are used for acquiring information of the patients. Results: Mean of age, gender, marital status, place for living, level of income of UD, BAD-D and control groups were similar. Statistically significant differences were observed in between UD, BAD-D and control groups, in terms of HRDS, TAS-20 and SF-36 scores. Mean group scores of UD and BAD-D group were higher than controls, in terms of all scales. However, mean points of UD and BAD-D groups were similar in terms of four scales. Patients with UD and BAD-D had positive relationship with TAS-20, BRDS and BDI; negative relationship between SF-36, significantly. In conclusion, it is found that alexithymia scores of UD and BAD-D groups were higher; quality of life scores were lower than controls. It is also observed that patients with higher alexithymia scores have more severe depressive symptoms and having a less sense of quality of life. Although our findings indicate that presense of alexithymia is important in depressive disorders, however no difference were found between alexithymia scores in patients with UD and BAD-D. Discussion: Alexithymia scores of all groups had positively related with depression, negatively related with quality of life. Our findings showed that, alexithymia is an important factor to the diagnosis of depressive disorders, however alexithymia is not a marker to make differential diagnosis of BAD-D and UD.
The Role of Authentic Orientation, Hope and Vitality in Psychological Symptoms and Affect: Investigation in a Clinical Sample
(Turkish Psychologists Assoc, 2019) Yalcindag, Bilge; Kahya, Yasemin
